Leptospirosis can involve which organ systems?

Leptospirosis can involve which organ systems?

• A. Renal and hepatic systems
• B. Nervous system only
• C. Musculoskeletal system only
• D. Integumentary system only

Answer: (A)

Leptospirosis classically targets the kidneys and liver. The infection often causes acute kidney injury from tubulointerstitial involvement and liver dysfunction that can produce jaundice and abnormal liver tests. This combination—renal and hepatic involvement—is the hallmark pattern. While it’s true that leptospira can affect other organs, including the nervous system or lungs in some cases, those manifestations are not the primary or most characteristic targets. So the organ systems most consistently involved are the renal and hepatic systems.

Leptospirosis classically targets the kidneys and liver. The infection often causes acute kidney injury from tubulointerstitial involvement and liver dysfunction that can produce jaundice and abnormal liver tests. This combination—renal and hepatic involvement—is the hallmark pattern. While it’s true that leptospira can affect other organs, including the nervous system or lungs in some cases, those manifestations are not the primary or most characteristic targets. So the organ systems most consistently involved are the renal and hepatic systems.